Pd-Catalyzed Highly Selective Three-Component Protocol for Trisubstituted Allenes
نویسندگان
چکیده
Herein we report the first example of Pd-catalyzed highly selective three-component reaction alkyn-1,4-diol dicarbonates, organoboronic acids, and malonate anions for efficient synthesis trisubstituted 2,3-allenyl malonates not readily...
منابع مشابه
Copper‐Catalyzed Borylative Cross‐Coupling of Allenes and Imines: Selective Three‐Component Assembly of Branched Homoallyl Amines
A copper-catalyzed three-component coupling of allenes, bis(pinacolato)diboron, and imines allows regio-, chemo-, and diastereoselective assembly of branched α,β-substituted-γ-boryl homoallylic amines, that is, products bearing versatile amino, alkenyl, and borane functionality. Alternatively, convenient oxidative workup allows access to α-substituted-β-amino ketones. A computational study has ...
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ژورنال
عنوان ژورنال: Chemical Science
سال: 2023
ISSN: ['2041-6520', '2041-6539']
DOI: https://doi.org/10.1039/d3sc01849k